The future of programmable RNA medicine

Led by Science. Driven by Data. Powered by AI.

Foundations     

The future of programmable RNA medicine

Led by Science. Driven by Data. Powered by AI.

Artificial Intelligence

We let our data be our guide.

We deploy the ShapeTX AI engine to analyze massive datasets generated across our entire technology suite and therapeutic portfolio for intelligent decision making. ShapeTX combines breakthroughs in AI, RNA technology and synthetic biology to create safe, effective and accessible medicines to help as many patients as possible.

Foundations     

RNA as Medicines

Programming the genetic code of life

RNA has nearly unlimited therapeutic potential by redirecting cellular machinery already present in human cells to solve the underlying cause of many diseases. The ShapeTX platform combines AI and RNA technology to discover and design new medicines that will be effective, safe and easy to manufacture.

Leveraging AI + RNA technology to discover programmable RNA medicines

Platform       

Payloads

Rewriting the digital code of RNA

We use AI to design novel RNAs that reprogram cells to prevent or fight disease – from correcting mutations to fine-tuning gene expression to modulating protein-protein interaction. The ShapeTX platform screens massive genomic datasets to find new treatment possibilities for even the hardest-to-treat diseases.

Platform       

Payloads

RNAfix®

Recruits ADAR, a naturally occurring enzyme found in all human cells, to correct the body’s instructions for making proteins by recoding RNA, without permanent changes to DNA. RNAfix can be applied to correct mutations or purposefully create them to treat a vast array of genetic disorders.

Platform       

Delivery

Incredibly precise delivery

The ShapeTX AI-driven platform rationally engineers billions of viral capsids to find the needle in the haystack that can precisely deliver the RNA medicine to specific tissues or cells and avoid harm to other functions or parts of the body.

Platform       

Manufacturing

Manufacturing, at any scale

ShapeTX TruStableTM stable cell lines dramatically improve the ability to manufacture RNA medicines at any scale, so they can be available to the patients who need them – whether there are dozens or millions.

A whole universe of

Possibility

Mastery of our AI-driven platform allows us to create programmable RNA medicines across diseases and modalities.

Explore the possibilities     ›

A whole universe of

Possibility

Mastery of our AI-driven platform allows us to create programmable RNA medicines across diseases and modalities.

Explore the possibilities     ›